Hexarelin- A Cornered Growth Hormone Until Now


Hexarelin, otherwise known as Exomerlin is a complex six peptide-like Growth Hormone Releasing Peptide-6. It is often stamped out from the screen because of its distinctive features, however, this black sheep sometimes overlooked for a few benefits. The gross underrated Hexarelin shouldn’t be sidelined, but rather studied to learn the positive effects and usability for athletes and bodybuilders due to its contribution to bone mineral density. This polypeptide is now considered at American Science Labs – GHRP 6 due to the ability to release more Growth Hormone from the pituitary gland when injected through intravenous, intranasal, subcutaneous and orally on animals.

The bioavailability is much higher with i.v and subcutaneous modes as per the literature, and hence it is a waste to administer nasal or oral. On top of that, one or two injects daily do not sound bearable in polite circles too. Hence, skin is the viable mode of administration. Many studies are being done on modified peptides and proteins, https://www.ncbi.nlm.nih.gov/pubmed/26126913 is the article where a study on recent advancements in immunomodulatory peptides are given. Hexarelin, according to the animal studies, the correspondent of the GHRP-6 trigger the release of Growth Hormone inside the body. Apart from that, being the most effective drug, it does not have the food-craving properties shown by these animals under investigation. Unlike most other class of drugs, the weight gain is found to be null when compared to other secretagogues after administering to animals. Hexarelin induces the release of Growth Hormone without affecting the deposition of fatty layers on cumulative administration.

Mechanism of Action of Hexarelin

Most of the ghrelin stimulating medicine endlessly binds to hormone receptors and retain a layer of fat within a short period of time. Whereas, Hexarelin, according to the simulated model studies does not have such detrimental effects on ‘hunger hormone’ ghrelin. It stimulates Growth Hormone This mechanism of action keeps heparin in the first line of choice of growth hormone secretory drug. The significant role of Hexarelin on Prolactin and ACTH cortisol releasing activity has been observed, however, the mainstream mechanism is yet to be discovered. A comparative study between the GHRP-2, 6 and 1 are also demonstrated, but so far, the results showed Hexarelin to be the most effective one among all three.

Recent studies on rats observed strange findings of Hexarelin on Cardiac receptors apart from the GH releasing benefits. This peptide, to a certain extent, can directly aid in cardioprotective pressure issues as well as healing of tissues of the heart. In children, injection of Hexarelin and Testosterone combined has elevated effects on Growth Hormone. This scientific data shall take its way to benefit the athletes in the future since the Hexarelin-Anabolic steroid combination induces response on growth hormone. The evidence collected by the researchers are not appreciable enough to find the total benefits, like muscle gain.

Hexarelin is similar to anabolic steroids but it does not come with any side effects to be bothered about. The peptide is a growth hormone releasing a resource that is devoid of side effects in animals. Sometimes side effects are seen in lab animals but these are mostly mild and do not produce any aggressive health effects.

Syphilis: Facts, Causes And Prevention

The number of people affected by Syphilis has increased considerably since 1995. It has gone double the number within a span of ten years. In most of the cases, it is the men who are affected and more than 90% of them seem to have the same sexual partners. Infection rates in women have come down rather rapidly. Last year 16,000 cases were reported to have been syphilis. However, these numbers could be wrong. One the reasons syphilis is increasing is because the usage of condoms has come down. The only way to get detected is by undergoing a test in any test centers such as a  STD clinic Pittsburgh. You can also check the website http://www.sandiegocounty.gov/hhsa/programs/phs/community_health_statistics/ for more information on syphilis cases.

The increase in numbers is something to be concerned about, because if left unattended it can result in acquiring HIV. The possibility of a syphilis infected person acquiring HIV is as high as 70% and there is no treatment for HIV at present. Syphilis is caused by a bacteria called as Treponema pallidum. It can enter the human body via any small openings and mostly it enters via sexual intercourse. Very rarely they spread via contact with other infected surfaces or skin and sometimes during delivery. Therefore, the possibility of getting infected by syphilis is more than you can imagine.

During the initial stages of the disease, a sore appears which is called as chancre. Even the sore takes weeks to appear after getting infected. The size of the sore can be large or small which is why many times it goes unnoticed. It does not cause any pain nor does it have any odor. It just appears as a shallow ulcer. Some people even get multiple sores like this various places in the infected area. They will disappear off on their own after time but they are capable of spreading quickly.

If this initial sore is left untreated, within weeks it can develop into flu-like symptoms accompanied by headache, muscle ache, sore throat, joint ache and low fever etc. The rashes that cover the mucous membrane of the skin are present in palms and also in the soles of the feet.

When the disease gets to this stage, most people seek medical help. If it is left as is even after this, then it can develop into serious complications after one or even 30 years. This late stage syphilis can affect any organ in the human body and it is capable of causing severe damage to the heart and brain.

One of the best methods to diagnose syphilis is by undergoing a blood test that can screen for any possible infections. Penicillin is known to be an effective drug against syphilis and the intensity of the treatment depends on the level of infection and stage of the disease. There are also alternate options available to patients who are allergic to penicillin. There are no vaccines for preventing the disease and the best method to avoid it is by following safe sexual practices